Methodologies for Scalable Production of High-Quality Purified Small Extracellular Vesicles from Conditioned Medium

Giovedì 18 maggio 2023 circa 1 minuti di lettura

Journal and Affiliations:

Methods in Molecular Biology, = 2023

Gabriella Andriolo, Lugano Cell Factory, Cardiocentro Ticino, EOC, Lugano

Elena Provasi, Lugano Cell Factory, Cardiocentro Ticino, EOC, Lugano

Andrea Brambilla, Lugano Cell Factory, Cardiocentro Ticino, EOC, Lugano

Stefano Panella, Cardiovascular Theranostics, Cardiocentro Ticino, Laboratories for Translational Research, EOC, Bellinzona

Sabrina Soncin, Lugano Cell Factory, Cardiocentro Ticino, EOC, Lugano

Viviana Lo Cicero, Lugano Cell Factory, Cardiocentro Ticino, EOC, Lugano

Marina Radrizzani, Lugano Cell Factory, Cardiocentro Ticino, EOC, Lugano

Lucia Turchetto, Lugano Cell Factory, Cardiocentro Ticino, EOC, Lugano

Lucio Barile, Cardiovascular Theranostics, Cardiocentro Ticino, Laboratories for Translational Research, EOC, Bellinzona e Facoltà di Scienze biomediche, USI, Lugano

Tags:
advanced therapy medicinal products (ATMP)
cardiac progenitors cells (CPC)
conditioned medium (CM)
extracellular vesicles (EV)
good manufacturing practices (GMP)
master cell bank (MCB)
production methods
quality control methods (QC) tangential flow filtration (TFF)
Authors:
Andrea Brambilla
Elena Provasi
Gabriella Andriolo
Lucia Turchetto
Lucio Barile
Marina Radrizzani
Sabrina Soncin
Stefano Panella
Viviana Lo Cicero
Link: https://link.springer.com/protocol/10.1007/978-1-0716-3203-1_7